Acyloin condensation
WordPress Facebook Instagram YouTube ACYLOIN CONDENSATION The acyloin condensation affords acyloins (α-hydroxy ketones by treating aliphatic esters with molten, highlydispersed sodium in hot xylene....
View ArticleOrganometallic Reagent
In this section we are going to look at one of the most important ways of making C-C bonds; using organometallics,such as organolithium and Grignard reagents in combination with carbonyl compounds. We...
View ArticleOrganometallics-2
1.Making carboxylic acid from organometallics and carbon dioxide Carbon dioxide reacts with organolithium and Grinard reagent to give carboxylate salt. Protonating the salt with acid gives carboxylic...
View ArticleAcidity and pKa
When an organic acid is dissolved in basic solution, the base deprotonates the acid to give an anion. For example aspirin which is not very soluble in water, but the sodium salt of it is more soluble,...
View ArticleSN1 and SN2 Reaction
SN1 Reaction 1. Introduction 2. Mechanism 3. Stereochemistry 4. Factors affecting kinetics of the reaction 1. Introduction Hughes and Ingold observed that the hydrolysis of tert-butyl bromide, which...
View ArticleSN2 Reaction,Mechanism, Nucleophilic Substitution Reaction
The nucleophilic substitution reaction in which the nucleophile attacks at the electrophilic carbon center from the back side, opposite to the departing group ( leaving group ), such reactions in...
View ArticleOrganic Chemistry |Stereochemistry | Conformational Analysis | NEET |JEE | 12...
Molecules that differ from each other by rotation about single bonds are called conformational isomers or conformer, sometimes called as rotamers. Derek H. R. Barton Noble Prize, jointly with Odd...
View ArticleStereoisomerism|Stereochemistry of Organic compounds | Conformational...
Angle strain Angle strain, makes a significant contribution to ring strain. In the cyclic alkanes discussed so far, the atoms of the ring are sp³ hybridized, with an ideal bond angle of 109.5″....
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